# BRAF (B-Raf proto-oncogene, serine/threonine kinase)

Entrez ID: 673
Chromosome (GRCh38): 7:140719327-140924976 (strand: -1)
UniProt: P15056
Type: protein-coding

## Summary

This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion.
Diseases: cardiofaciocutaneous syndrome, Noonan syndrome, melanoma, Noonan syndrome with multiple lentigines, cancer
Drugs: ENCORAFENIB, VEMURAFENIB, REGORAFENIB, DABRAFENIB MESYLATE
## Aliases

B-RAF1, BRAF1, NS7, RAFB1
More:  biomcp get gene BRAF pathways ontology diseases
All:   biomcp get gene BRAF all
See also:
  biomcp search variant -g BRAF
  biomcp search article -g BRAF
  biomcp search drug --target BRAF
  biomcp gene trials BRAF

[NCBI Gene](https://www.ncbi.nlm.nih.gov/gene/673) | [UniProt](https://www.uniprot.org/uniprot/P15056) | [Ensembl](https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000157764) | [OMIM](https://www.omim.org/entry/164757)

