# Clinical Trial Finder Report

Query: BRCA1 breast cancer
Generated: 2026-03-19T16:48:46+00:00
Trials found: 20 (5 recruiting)

Metric | Value
--- | ---
Total trials | 20
Recruiting now | 5

## Trials

20 trials
COMPLETED Registry of Mastectomy for Breast Cancer Risk Reduction
NCT00555503 | Phase: N/A | 2007-11 -- 2014-01
Quality of Life, Mastectomy, Breast Neoplasms
RECRUITING Pancreatic Cancer Genetics
NCT01102569 | Phase: N/A | 2008-01 -- 2027-12
Pancreatic Cancer
ACTIVE_NOT_RECRUITING Niraparib + Dostarlimab In BRCA Mutated Breast Cancer
NCT04584255 | Phase: PHASE2 | 2020-12-18 -- 2029-07-17
Stage I Breast Cancer, Stage II Breast Cancer, Stage III Breast Cancer
UNKNOWN Abbreviated Breast MRI for Second Breast Cancer Detection in Women With BRCA Mutation Testing
NCT03475979 | Phase: N/A | 2018-05-01 -- 2022-06
Breast Cancer, BRCA1 Mutation, BRCA2 Mutation
COMPLETED Randomized CT to Evaluate Efficacy of Neoadjuvant Chemotherapy Customized by Levels of BRCA1-HER2 Negative Breast Cancer
NCT02365805 | Phase: PHASE2 | 2014-04 -- 2016-10-10
Breast Cancer
UNKNOWN A Study of Fluzoparib±Apatinib Versus Chemotherapy Treatment of Physician's Choice in HER2-negative Metastatic Breast Cancer Patients With Germline BRCA Mutation
NCT04296370 | Phase: PHASE3 | 2020-07-13 -- 2025-06-30
Treatment in HER2-negative Metastatic Breast Cancer Patients With Germline BRCA Mutation
COMPLETED Use of Recombinant hCG to Prevent Breast Cancer in BRCA1 and BRCA2 Carriers
NCT03495609 | Phase: PHASE4 | 2016-02-17 -- 2018-12-18
hCG, BRCA1 Mutation, BRCA2 Mutation
RECRUITING SHARON: A Clinical Trial for Metastatic Cancer Using Chemotherapy and Patients' Own Stem Cells
NCT04150042 | Phase: PHASE1 | 2021-01-13 -- 2028-12
Pancreatic Adenocarcinoma Metastatic, BRCA1 Mutation, BRCA2 Mutation
RECRUITING Serum Biomarkers to Characterize the Effects of Therapy on Ovarian Reserve in Premenopausal Women With Early-stage Breast Cancer or BRCA Mutations
NCT00823654 | Phase: N/A | 2009-01 -- 2027-01
Breast Cancer
UNKNOWN Breast Cancer After Ovarian Cancer During and/or After Therapy: Genomic Evaluation
NCT05763472 | Phase: N/A | 2022-03-01 -- 2023-06-01
BRCA-Associated Breast Carcinoma
COMPLETED Phase I of Carboplatin-Olaparib Followed by Olaparib Monotherapy in Advanced Cancer
NCT02418624 | Phase: PHASE1 | 2015-05 -- 2019-01
Breast Cancer, Ovarian Cancer, Advanced Cancer
UNKNOWN Study of Quality of Life Post Salpingo-oophorectomy in BRCA1/2 & PALB2 Mutation Carriers (BRCA-HRT)
NCT05409222 | Phase: N/A | 2020-03-12 -- 2023-10
Hereditary Breast and Ovarian Cancer
COMPLETED Study Evaluating Efficacy And Tolerability Of Veliparib in Combination With Temozolomide (TMZ) or In Combination With Carboplatin and Paclitaxel Versus Placebo in Participants With Breast Cancer Gene (BRCA)1 and BRCA2 Mutation and Metastatic Breast Cancer
NCT01506609 | Phase: PHASE2 | 2012-01-23 -- 2020-09-02
Metastatic Breast Cancer
UNKNOWN Studying Breast Cancer Risk in Women Who Are BRCA1/BRCA2 Mutation Carriers
NCT00897455 | Phase: N/A | 2008-04 -- ?
brca1 Mutation Carrier, brca2 Mutation Carrier, Breast Cancer
ACTIVE_NOT_RECRUITING Genetic Risk Estimations for Influencing Decision Making in Women at High Risk of Breast Cancer, GENRE 2 Study
NCT04474834 | Phase: N/A | 2019-10-17 -- 2029-12-15
Breast Cancer
RECRUITING MEASUREMENT OF CIRCULATING MUTATION BURDEN
NCT06792721 | Phase: N/A | 2025-07-04 -- 2027-12-30
Breast Carcinoma, Genetic Predisposition to Cancer, BRCA Mutation
RECRUITING Novel Neoadjuvant and Adjuvant Strategy for Germline BRCA 1/2 Mutated Triple Negative Breast Cancer
NCT05485766 | Phase: PHASE2 | 2024-07-16 -- 2028-09-30
Triple Negative Breast Neoplasms, Triple Negative Breast Cancer, Breast Neoplasms
NO_LONGER_AVAILABLE Expanded Access With ABT-888 (Veliparib) to Treat Metastatic Breast Cancer
NCT02985658 | Phase: N/A | ? -- ?
Metastatic Breast Cancer With BRCA 1 or BRCA 2 Genetic Mutation, Triple-Negative Breast Cancer
ENROLLING_BY_INVITATION Strategy for Management of Patients With Hereditary Cancer Syndromes (HCS) in a Rural Environment
NCT07381985 | Phase: NA | 2023-12-29 -- 2027-12-01
Hereditary Cancer Syndromes, BRCA1 Hereditary Breast and Ovarian Cancer Syndrome, Lynch Syndrome
TERMINATED A Phase III Trial of Niraparib Versus Physician's Choice in HER2 Negative, Germline BRCA Mutation-positive Breast Cancer Patients
NCT01905592 | Phase: PHASE3 | 2014-02-25 -- 2021-10-26
Neoplasms, Breast, Carcinoma of Breast, Human Epidermal Growth Factor 2 Negative Carcinoma of Breast
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