---
name: journal-cell-cysteines-metabolic-fork-20260612
description: >
  学术期刊学习笔记：Cell - Cysteine’s metabolic fork: Sulfur partitioning shapes T cell function
  蒙多每日期刊学习系统自动提取。
version: 1.0.0
author: mundo-journal-bot
priority: LOW
auto_activate: MANUAL
category: journal-learnings
source: Cell
published: 2026-06-11
learned: 2026-06-12
---
# Cysteine’s metabolic fork: Sulfur partitioning shapes T cell function

**来源**: [Cell](https://www.cell.com/cell/fulltext/S0092-8674(26)00587-8?rss=yes)
**学习日期**: 2026-06-12

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## 摘要

Cellular senescence comprises diverse cell states emerging across human tissues during aging and disease. Integrating single-cell and spatial multi-omics with AI-driven analyses enables systematic mapping of senescent cell heterogeneity (“senotypes”), revealing tissue-specific programs and microenvironmental interactions. These advances provide frameworks for biomarker discovery and development of targeted senotherapeutic strategies.

## 关键发现

1. Integrating single-cell and spatial multi-omics with AI-driven analyses enables systematic mapping of senescent cell heterogeneity (“senotypes”), revealing tissue-specific programs and microenvironmental interactions
2. These advances provide frameworks for biomarker discovery and development of targeted senotherapeutic strategies

## 蒙多笔记

> 蒙多从此文中学到：Cysteine’s metabolic fork: Sulfur partitioning sha...
> 此知识已纳入蒙多的学术知识库。

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